Quantitative Evaluation of Compliance with Recommendation for Sulfonylurea Dose Co-Administered with DPP-4 Inhibitors in Japan

After the launch of dipeptidyl peptidase-4 (DPP-4), a new oral hypoglycemic drug (OHD), in December 2009, severe hypoglycemia cases were reported in Japan.Although the definite cause was unknown, co-administration with sulfonylureas (SU) was suspected as one of the potential risk factors.The Japan Association for Diabetes Education and Care (JADEC)

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Spiritualistic Humanistic Communication Strategy on Learning Aqidah Akhlaq at Madrasah Ibtidaiyah Negeri 1 Yogyakarta, Indonesia

This study discusses the communication strategy in learning Aqidah Akhlaq to foster humanistic values and spiritualistic intelligence of learners in religious Elementary School Madrasah Ibtidaiyah Negeri (MIN) 1 Yogyakarta.This study used a qualitative approach with case study method.Data were collected by in-depth interview, Desk observation, and

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Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1 G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner

Abstract Background Burgeoning evidence highlights seminal roles for microglia in the pathogenesis of neurodegenerative diseases including amyotrophic lateral sclerosis (ALS).The receptor for advanced glycation end products (RAGE) binds CONDITIONING MOUSSE ligands relevant to ALS that accumulate in the diseased spinal cord and RAGE has been previou

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